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For example, ROS can facilitate the extrinsic apoptosis pathway through negative regulation of the cellular FLICE-inhibitory protein (Wang et al., 2008) and can induce intrinsic apoptosis pathways by triggering quick release of Cyt-c (Madesh and Hajnoczky, 2001) and regulating the Bcl-2 protein family (Li et al., 2011), and AMPK can be activated by AMPK kinase after H 2 O 2 treatment, which also results in autophagy induction ( Given the strong relationship between ROS and cell death, regulating ROS generation upward or controlling oxidative defense downward has become central for new cancer treatments, which have been enhanced by the finding that cancer cells process a higher level of ROS than do healthy cells (Tafani et al., 2016), can lead to two opposite outcomes: the promotion of cancer and its suppression

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Alzheimers disease therapeutics: Current strategies and future directions

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Asam lemak merupakan detoksifikasi utama dan antioksidan utama tubuh, melindungi sel-sel kita dan membuat metabolisme energi kita berjalan dengan baik